Our Focus

We believe the world is changing faster than ever.

We have seen the information + computing + people thesis transform the business of investment management, and we support companies applying it to other industries.

Our Approach

Early Stage. Across Industries. Deep Expertise.

We invest early—from seed to series B—and stick around as a long-term partner. From dev tools to biotech, we support data- and computing- driven transformation using our expertise in machine learning, engineering, and more.

Our Advantage

Science and technology are in our DNA.

Our team and the over 1,600 employees and 200 PhDs we’re lucky to call colleagues bring a wealth of extraordinary experience to every company we work with.

From Our Blog

Announcing Our Investment in Hexagon Bio’s $47M Series A

We are thrilled to announce that Two Sigma Ventures is investing in Hexagon Bio’s $47 million Series A alongside The Column Group, 8VC, and Luma Bio.

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5 Healthcare Predictions for the Post-COVID-19 World

Though we’ve had our fair share of global health outbreaks in recent history, COVID-19 most closely parallels the 1918 flu pandemic in scale and impact—a once-in-a-hundred-years type of black swan event.

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Introducing Two Sigma Ventures III, Our $288M Fund

We’re excited to announce the close of Two Sigma Ventures III, a $288M fund that we’ll use to continue backing early-stage technology companies pushing the boundaries of what’s possible with data science and advanced computing across all industries.

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New York

Two Sigma

100 Avenue of the Americas
3rd Floor
New York, NY 10013

T +1 212 625 5700
F +1 212 625 5800